General Hospital spoilers reveal Lucky Spencer (Jonathan Jackson) will reunite with Laura Collins (Genie Francis) this week as she heads back from her search for him with relief in her heart that he is not only okay, but home to potentially save his little sister’s life.

But that’s where the relief could come to a screeching halt. Everyone has been banking on Lucky being the best possible match, but rumor has it this liver transplant isn’t going to go as expected.

While a full sibling was always Lulu Falconeri’s (Alexa Havins) best bet at surviving this ordeal, there is still a long road ahead when it comes to the transplant being a success. Will the Spencer family make it through when Lucky’s and Lulu’s luck runs out?

General Hospital Spoilers — From Grief  To Relief

Laura has been reeling with grief ever since the moment she got the call from Lulu’s doctor at the long-term care facility that something was wrong with her. Learning that she needed a liver transplant to survive rocked Laura to her core.

Immediately, she assumed Nikolas Cassadine (Adam Huss) would be their easiest option to manage Lulu’s liver failure, but finding out quickly that he wasn’t a viable match left her crippled. She knew finding Lucky wouldn’t be easy. But now that he’s home, she may be able to breathe again. Maybe.

GH Spoilers – Hint Laura Collins Is Afraid To Get Her Hopes Up

At the same time as she’s going to be thrilled to see her son after almost ten long years apart, Laura will be concerned that the other shoe is going to drop at any moment.

Will she find the nerve to table her anxiety over whether a liver transplant from Lucky will pan out long enough to enjoy her son being home?

If not, her distance and distracted demeanor could leave Lucky feeling like his mom is holding it against him that he’s been gone for so long. Is she?

General Hospital Spoilers — Who Will Be Lulu’ Spencers Saving Grace?

If Laura is correct and the other shoe does fall, then Lucky won’t ultimately be able to save Lulu’s life, but that doesn’t mean someone else won’t come in at the eleventh hour to do it. Just who might that be though?

When a biological full sibling gives her the best odds of survival, and neither of her brothers are a match, Laura and everyone else may be devastated and lose hope. But some fans are chattering that the real hero in the end may be someone else who doesn’t survive — Sam McCall (Kelly Monaco).

That would make for an awfully bittersweet shocking death for Sam while creating a total rebirth for Lulu. Would Dante Falconeri (Dominic Zamprogna) ever be able to replace all that loss and gain at the same time?

Stay tuned for more GH news and spoilers just ahead.