General Hospital (GH) spoilers and updates reveal John “Jagger” Cates (Adam J. Harrington) and Ava Jerome (Maura West) are quickly racking up a list of enemies for each of them.

They’ve each gotten under the skin of practically everyone in Port Charles, sure signs there’s a murder mystery looming-question is, who’s going down-Ava or Cates, or maybe both of them?

General Hospital Spoilers – John Cats’s Collecting More Hate Than Evidence

Jagger has not only been the main reason why Jason Morgan (Steve Burton) has been separated from his loved ones for almost three years, but he also continues to blackmail him.

He is continuing to hold the infamous Carly Spencer (Laura Wright) audio over his head and threatening her with RICO charges knowing Jason cares about his best friend.

Now that Carly knows the extent of her friend’s sacrifice, she is furious with John for using the recording to threaten her with prison.

In addition to his clashes with Sonny Corinthos (Maurice Benard) and Anna Devane (Finola Hughes), John has also rubbed Sam McCall (Kelly Monaco) the wrong way.

This is due to Jason’s long disappearance and being presumed dead, even though she mostly blames Jason and Carly for the sacrifice he made.

GH Spoilers – Ava Jerome’s List Of Enemies Is Growing Longer, Although She And Jagger Cates Have Some In Common

Ava, the art gallery owner, has never been one to win a popularity contest in town-she has been scheming and manipulating several key players in Port Charles.

Recently, she leaked an audio clip to the press of Natalia Rogers-Ramirez (Eva LaRue) making disparaging remarks about the LGBTQ+ community, all to get back at Sonny.

On top of that, she convinced Sonny to push away his loved ones, played a role in Alexis Davis’ (Nancy Lee Grahn) disbarment, and tampered with Sonny’s bipolar medication.

Let’s not forget about John’s investigation of Pikeman, which caught the attention of Jack Brennan (Charles Mesure) and Valentin Cassadine (James Patrick Stuart).

Now, Ava and Sonny are caught up in a heated custody battle as well, over Avery Jerome-Corinthos (Ava and Grace Scarola) with Jagger helping.

General Hospital Spoilers – A Laundry List Of Suspects If Either One’s Killed

With all that being said, when it comes to John and Ava, there are plenty of individuals who might wish for their permanent disappearance.

Could one of them or both of them end up being a victim of murder-or even take each other down in a shootout? It has been a lingering suspicion that Ava would meet her demise on the soap opera.

The writers have truly backed her into a corner, and it’s hard to imagine how she will come out of this unharmed unless she takes the witness protection route like her late brother.

Tampering with Sonny’s medication is a significant mistake that could lead to serious repercussions once the truth comes to light.

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